For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.

For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.

To Prepare:

Review the information provided and answer questions posed in the case study
When recommending a medication, write out a complete prescription for the medication
Whenever possible, use clinical practice guidelines in developing your answers when possible
Include at least three references to support your answer and cite them in APA format.

LIST REFERENCES AFTER EACH SCENARIO. They should be peer reviewed within the last 3 years.

Directions: For each of the scenarios below, answer the questions using your required learning resources, Medscape, and clinical practice guidelines (ie AHA, ACC, ADA, GINA). When recommending medications, write out a complete prescription for each medication. What order would you send to a pharmacy? Include drug, dose, route, frequency, # dispensed (days supply), refills, special instructions etc. Also state if you would continue, discontinue or taper the patient’s current medications (if applicable). Use at least 3 sources for each scenario and cite sources using APA format. LIST REFERENCES AFTER EACH SCENARIO.

SCENARIO 1

What are the errors in the following prescriptions (1 per prescription)? Rewrite each prescription correctly. What is each medication’s classification and mechanism of action (MOA)?

fentanyl transdermal patch 12 mcg/hr Apply 1 patch to skin every 72 hours #10 patches 1 RF
Skyrizi 600 mg/10 mL IV infused over 1 hour at weeks 0, 4, 8 and 12 for Crohn’s disease #1 vial 3 RF
allopurinol 300 mg PO QID #120 0 RF
adalimumab (Humira) 120 mg SQ inject every other week #2 syringes 1 RF
bupropion XL 150 mg PO BID for smoking cessation #60 1 RF


SCENARIO 2

Zolpidem has a half-life of 3 hours. If a patient takes 10 mg at 21:00, what will the blood level be at 06:00? Name 3 antidepressants/antipsychotics you might prescribe for patients with co-existing depression and insomnia. What is their MOA? Include complete medication orders and patient monitoring for each of the 3 medications.



SCENARIO 3

Match the following patients to the most appropriate antidepressant for their symptom cluster. Each medication option is used once. Include MOA, medication side effects, and a medication order for at least 1 of the patients.

Patient

Presentation

1

fibromyalgia, insomnia, no depression

2

diabetic neuropathy, fatigue, depression

3

postherpetic neuralgia, poor appetite, insomnia

4

chronic musculoskeletal pain, anxiety, hot flashes

5

fibromyalgia, no mood disorder, prefers non-sedating



Medication options:

A. amitriptyline

B. duloxetine

C. mirtazapine

D. venlafaxine

E. milnacipran





SCENARIO 4

OH is an 9-year-old male brought in by his father due to concerns about behavior and school performance. His teacher reports that OH is frequently out of his seat, talks excessively, blurts out answers, and has difficulty completing tasks and following directions. At home, he often loses homework, seems forgetful, and struggles to stay focused on activities like reading. Growth and development are age-appropriate. He sleeps about 9 hours per night but still wakes up feeling tired. There are no signs of anxiety, depression, or other mood disorders. What is the most likely diagnosis? What is an appropriate first-line medication (include complete medication order)? What monitoring parameters should be considered during treatment?

IOS HERE

LEARNING RESOURCES:
Rosenthal, L. D., & Burchum, J. R. (2025). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (3rd ed.). Elsevier.
Chapter 24, “Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics” (pp. 180–191)
Chapter 32, “Substance Use Disorders I: Basic Considerations” (pp. 252–257)
Chapter 33, “Substance Use Disorders II: Alcohol” (pp. 257–264)
Chapter 34, “Substance Use Disorders III: Nicotine and Smoking” (pp. 264–269)
Chapter 35, “Substance Use Disorders IV: Major Drugs of Abuse Other Than Alcohol and Nicotine” (pp. 269–280)
Chapter 59, “Cyclooxygenase Inhibitors: Nonsteroidal Antiinflammatory Drugs and Acetaminophen” (pp. 500–509)
Chapter 61, “Drug Therapy of Rheumatoid Arthritis” (pp. 519–533)
Chapter 62, “Drug Therapy for Gout” (pp. 534–539)